Contrave (Bupropion/Naltrexone) for Obesity | MyObesityTeam

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Contrave is a prescription drug approved by the Food and Drug Administration (FDA) for chronic weight management in conjunction with a reduced-calorie diet and exercise. Contrave may be prescribed for adults with a body mass index (BMI) of 30 or greater. Adults with a BMI of 27 or greater may be considered candidates for Contrave if they have at least one weight-related medical condition. Contrave is a combination of two drugs, Naltrexone and Bupropion.

Naltrexone is an opiate antagonist. It is believed that Naltrexone works by decreasing food cravings. Bupropion is an antidepressant that causes weight loss as a side effect. It is believed that Bupropion works by suppressing the appetite.

How do I take it?
Prescribing information states that Contrave should be taken once or twice a day.

Contrave comes in tablet form.

Side effects
The FDA-approved label for Contrave lists common side effects including headache, dizziness, insomnia, dry mouth, nausea, vomiting, diarrhea, and constipation.

Rare but serious side effects listed for Contrave include liver problems, glaucoma, seizures, increased blood pressure, and suicidal thoughts and behavior.

For more details about this treatment, visit:
Contrave – Orexigen

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