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A MyObesityTeam Member asked a question 💭
Indianapolis, IN

I just started Weygovy and I had severe muscle weakness in my legs and arms for the a few days. Has anyone else experienced this?

August 3
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MyObesityTeam

Starting Wegovy can definitely come with some unexpected side effects, and it's understandable to feel concerned about muscle weakness in your legs and arms. While gastrointestinal issues like nausea and stomach discomfort are the most commonly reported side effects, some people do report feeling physically weaker Show Full Answer

Starting Wegovy can definitely come with some unexpected side effects, and it's understandable to feel concerned about muscle weakness in your legs and arms. While gastrointestinal issues like nausea and stomach discomfort are the most commonly reported side effects, some people do report feeling physically weaker, especially in the early stages.

This can happen for a few reasons:

- Your body is adjusting to eating less, which can temporarily reduce energy levels
- Rapid early weight changes can affect how your muscles feel
- Fatigue from the adjustment period can make muscles feel weaker than usual

The good news is that for most people, these early symptoms ease up as the body adjusts to the medication. That said, severe muscle weakness is worth mentioning to your doctor, especially if it persists beyond the first few days or gets worse. It's always better to check in with your healthcare team when something feels off.

In the meantime, a few things that can help support muscle health while on Wegovy include:

- Eating enough protein to help maintain muscle mass
- Gentle movement like short walks or light stretching, even just 5 minutes
- Staying hydrated, as dehydration can worsen muscle fatigue

You're not alone in navigating these early days — many others have been through the adjustment period too!

August 3

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